Anticancer Activities of Surfactin and Potential Application of Nanotechnology Assisted Surfactin Delivery
نویسندگان
چکیده
منابع مشابه
Anticancer Activities of Surfactin and Potential Application of Nanotechnology Assisted Surfactin Delivery
Surfactin, a cyclic lipopeptide biosurfactant produced by various strains of Bacillus genus, has been shown to induce cytotoxicity against many cancer types, such as Ehrlich ascites, breast and colon cancers, leukemia and hepatoma. Surfactin treatment can inhibit cancer progression by growth inhibition, cell cycle arrest, apoptosis, and metastasis arrest. Owing to the potent effect of surfactin...
متن کاملSurfactin isoforms from Bacillus coagulans.
Bacillus coagulans has been found to produce several surfactins that are powerful lipopeptide surfactants. Four main components with molecular weights 1007, 1021 and 1035 Da were separated. Their structures have been confirmed by spectrometric and spectroscopic studies and by acid hydrolysis. The compounds were found to represent two pairs of surfactin isoforms in which beta-hydroxy-iso-C14 or ...
متن کاملSurfactin – Novel Solutions for Global Issues
The constant demand for new, effective therapeutic agents has triggered intensive research in the field of diverse antimicrobials of natural origin. These compounds are synthesized by all forms of life and have important biomedical and biotechnological properties, and are thus widely considered a potential solution to the growing problem of resistance to conventional antibiotics, fungal infecti...
متن کاملeffect of postharvest application of chitosan and calcium chloride on decay and quality attributes of sweet cherry
چکیده ندارد.
15 صفحه اولStructural and functional organization of the surfactin synthetase multienzyme system.
By gel filtration of a crude extract of Bacillus subtilis ATCC 21332 and OKB 105, the multienzyme system that forms the lipoheptapeptide surfactin was separated into three enzyme fractions, E1, E2, and E3. E1, which appeared near the exclusion limit of the column, activates all amino acid components of surfactin as aminoacyladenylates and thioesters according to the thioester mechanism. In addi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Frontiers in Pharmacology
سال: 2017
ISSN: 1663-9812
DOI: 10.3389/fphar.2017.00761